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Staging of colon cancer, see table
stages of carcinomas.
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| Tubulopapillary carcinoma (De-novo-carcinoma) |
 |
This is a
de-novo-carcinoma with a diameter
of 1,5 cm. Most carcinomas originate from adenomas
(adenoma-carcinoma-sequence). The cause of
the de-novo-carcinomas is unknown. Correlations to
HNPCC, ulcerative Colitis and non tropical sprue
are reported. On the other hand flat adenomas were
identified as precursors, thus questioning the hypothesis
of de-novo-carcinogenesis. HNPCC = Hereditary
Non Polyposis
Colorectal Carcinoma
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