| Deposits of pathological paraproteins |
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Polypoid
tumors with multiple superficial white dots are found in
the gastric
antrum. Endosonography identifies the lesions as mere
thickening of the
gastric mucosa ( up to 1 cm). Snare biopsy reveals a
deposition of light chain
proteins with a concomitant neutrophilic inflammation.
Pathoprotein deposition usually occurrs in proliferative,
lymphatic disorders or
with generalized light chain deposition disease. A
thorough diagnostic workup failed to show extra- gastric manifestations.
Progressive disease necessitated gastrectomy. Histology,
again only showed
protein deposition, no lymphoma. Thus a very rare isolated,
idiopathic, gastric
light chain deposition disease was diagnosed.
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