| Granular cell tumor |
 |
In
the lower section of the picture a minute
polypoid, yellowish tumor is shown. Histology
reveals a granular cell tumor. The tumors are
thought to originate from Schwann- cells.
The tumor is mostly benign, but also shows
malignant behaviour in very rare cases. It
makes up 0,5-5% of all benign esophageal
tumors. Histology shows an unstructered
pattern of tumor cells with an eosinophilic,
granular cytoplasma and a small nucleolus.
In immunhistochemic studies antibodies react with vimentin, protein S100 and neuron
specific enolase.
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